HitPredict

Interactor 1: SNW1 (Q13573)
SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein)
Gene: SNW1

Interactor 2: RBM22 (Q9NW64)
Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22) (Zinc finger CCCH domain-containing protein 16)
Gene: RBM22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	33961781, 34133714
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071007 - U2-type catalytic step 2 spliceosome and 1 others more... GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 420
+	Dm
		764027 BX42_DROME (1-533): 0: 644: 60.40		Q95RB1_DROME (1-399): 3.54e-111: 334: 57.50
+	Hs
		516501 SNW1_HUMAN (1-536): 0: 752: 100.00		PABP1_HUMAN (105-316): 1.37e-31: 128: 15.74
+	Hs
		963514 SNW1_HUMAN (1-536): 0: 752: 100.00		TIAR_HUMAN (107-361): 1.74e-30: 122: 12.64
+	Hs
		165466 SNW1_HUMAN (1-536): 0: 752: 100.00		SR140_HUMAN (227-354): 8.9e-13: 72.2: 22.63
+	Sp
		953355 PRP45_SCHPO (3-508): 0: 545: 42.27		CWC2_SCHPO (139-318): 8.87e-14: 74.5: 22.28
+	Sc
		655704 PRP45_YEAST (115-496): 3.27e-99: 306: 26.80		SLT11_YEAST (21-292): 1.39e-77: 246: 23.18
+	Sc
		376667 PRP45_YEAST (115-496): 3.27e-99: 306: 26.80		PABP_YEAST (221-316): 1.12e-13: 74.8: 20.59