Interactor 1: STIM1 (Q13586)
Stromal interaction molecule 1
Gene: STIM1
Interactor 2: ORAI1 (Q96D31)
Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A)
Gene: ORAI1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.755 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22446186, 35439114, 21876174, 19706554, 22451904, 19249086, 30481768, 20418871, 24996186, 24954132 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, ubiquitin reconstruction, pull down, molecular sieving, atomic force microscopy |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002115 - store-operated calcium entry GO:0005886 - plasma membrane GO:0044853 - plasma membrane raft GO:0045762 - positive regulation of adenylate cyclase activity GO:0051924 - regulation of calcium ion transport |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
