HitPredict

Interactor 1: STIM1 (Q13586)
Stromal interaction molecule 1
Gene: STIM1

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 1620
+	Hs
		1350041 STIM2_HUMAN (49-643): 0: 826: 51.93		ALK_HUMAN (1-1620): 0: 1883: 100.00
+	Hs
		434190 STIM1_HUMAN (1-685): 0: 1059: 100.00		RET_HUMAN (842-1477): 4.8e-137: 455: 23.56
+	Hs
		665597 STIM1_HUMAN (1-685): 0: 1059: 100.00		EPHB2_HUMAN (938-1436): 2.19e-123: 416: 23.26
+	Hs
		609279 STIM1_HUMAN (1-685): 0: 1059: 100.00		FGFR3_HUMAN (952-1449): 6.42e-121: 401: 26.31
+	Hs
		445849 STIM1_HUMAN (1-685): 0: 1059: 100.00		ROS1_HUMAN (1039-1461): 3.68e-112: 397: 37.75
+	Hs
		169175 STIM1_HUMAN (1-685): 0: 1059: 100.00		MUSK_HUMAN (983-1391): 2.02e-118: 396: 29.98
+	Hs
		507985 STIM1_HUMAN (1-685): 0: 1059: 100.00		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		411379 STIM1_HUMAN (1-685): 0: 1059: 100.00		INSR_HUMAN (973-1436): 1.01e-112: 392: 34.25
+	Hs
		435635 STIM1_HUMAN (1-685): 0: 1059: 100.00		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		537738 STIM1_HUMAN (1-685): 0: 1059: 100.00		INSRR_HUMAN (1082-1384): 2.38e-70: 262: 43.46
+	Hs
		384799 STIM1_HUMAN (1-685): 0: 1059: 100.00		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		1040115 STIM1_HUMAN (1-685): 0: 1059: 100.00		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03
+	Hs
		434300 STIM2_HUMAN (49-643): 0: 826: 51.93		RET_HUMAN (842-1477): 4.8e-137: 455: 23.56
+	Hs
		508240 STIM2_HUMAN (49-643): 0: 826: 51.93		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		411514 STIM2_HUMAN (49-643): 0: 826: 51.93		INSR_HUMAN (973-1436): 1.01e-112: 392: 34.25
+	Hs
		435788 STIM2_HUMAN (49-643): 0: 826: 51.93		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		1081633 STIM2_HUMAN (49-643): 0: 826: 51.93		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03