HitPredict

Interactor 1: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Interactor 2: LAR1B (Q659C4)
La-related protein 1B (La ribonucleoprotein domain family member 1B) (La ribonucleoprotein domain family member 2) (La-related protein 2)
Gene: LARP1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 282 Hs			1 914
+	Hs
		516553 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		LAR1B_HUMAN (1-914): 0: 921: 100.00
+	Hs
		1040345 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		1031367 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		516561 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		516568 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		LARP4_HUMAN (114-703): 1.5e-97: 323: 13.29
+	Hs
		1040370 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		LAR4B_HUMAN (95-701): 2.54e-81: 280: 10.36
+	Hs
		1031407 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		LAR4B_HUMAN (95-701): 2.54e-81: 280: 10.36
+	Hs
		516616 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		LAR4B_HUMAN (95-701): 2.54e-81: 280: 10.36
+	Hs
		403212 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		LA_HUMAN (215-628): 1.98e-59: 210: 17.78
+	Hs
		1040337 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		1116304 PAP1L_HUMAN (1-272): 4.36e-38: 143: 14.59		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		1031352 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		516541 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		1116542 PABP3_HUMAN (1-267): 3.29e-34: 132: 13.77		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		925050 TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	At
		790116 PABP2_ARATH (1-119): 8.99e-10: 60.9: 9.24		LRP6C_ARATH (130-445): 7.11e-55: 199: 14.83
+	At
		285478 PABP8_ARATH (1-119): 2.24e-11: 65.9: 5.04		LRP6B_ARATH (111-447): 3.39e-49: 185: 12.36
+	At
		285476 PABP2_ARATH (1-119): 8.99e-10: 60.9: 9.24		LRP6B_ARATH (111-447): 3.39e-49: 185: 12.36
+	Hs
		1047867 CIRBP_HUMAN (121-193): 2.19e-10: 60.1: 58.90		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Sc
		376650 PABP_YEAST (12-109): 4.14e-09: 59: 9.18		SRO9_YEAST (5-275): 1.31e-28: 121: 19.65