HitPredict

Interactor 1: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Interactor 2: PUF60 (Q9UHX1)
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)
Gene: PUF60

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 282 Hs			1 559
+	Hs
		1031490 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		PUF60_HUMAN (1-559): 2.1e-103: 324: 100.00
+	Hs
		1040327 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1031328 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		516518 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1020251 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		1040382 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		PABP5_HUMAN (133-308): 3.43e-45: 165: 23.86
+	Hs
		1119141 PAP1L_HUMAN (1-272): 4.36e-38: 143: 14.59		PABP5_HUMAN (133-308): 3.43e-45: 165: 23.86
+	Hs
		1020249 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		516484 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		516635 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		PABP5_HUMAN (133-308): 3.43e-45: 165: 23.86
+	Hs
		474022 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		PAB4L_HUMAN (479-559): 3.69e-14: 76.1: 20.99
+	Hs
		1031413 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		CELF1_HUMAN (98-214): 1.29e-17: 87.5: 26.50
+	Hs
		516621 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		CELF1_HUMAN (98-214): 1.29e-17: 87.5: 26.50
+	Hs
		1031314 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516502 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		474021 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		PAB4L_HUMAN (479-559): 3.69e-14: 76.1: 20.99
+	Hs
		516689 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		PABP3_HUMAN (479-559): 6.17e-13: 73.4: 19.75
+	Hs
		516339 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		516495 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64