HitPredict

Interactor 1: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Interactor 2: SRPK3 (Q9UPE1)
SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)
Gene: SRPK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 282 Hs			1 567
+	Hs
		625415 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		CDK2_HUMAN (274-566): 4.84e-82: 260: 17.97
+	Zm
		11850 A0A1D6II08_MAIZE (6-277): 2.47e-48: 169: 15.07		A0A1D6FHK3_MAIZE (31-336): 8.08e-73: 239: 17.54
+	Hs
		942638 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		516362 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		CDK2_HUMAN (274-566): 4.84e-82: 260: 17.97
+	Zm
		9779 A0A1D6EZQ5_MAIZE (6-277): 7.27e-46: 162: 15.07		A0A1D6FHK3_MAIZE (31-336): 8.08e-73: 239: 17.54
+	Hs
		516460 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		942631 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		1040371 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		DYRK2_HUMAN (344-565): 4.02e-65: 224: 25.82
+	Hs
		833877 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Hs
		516419 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		GSK3B_HUMAN (23-336): 1.58e-67: 226: 16.87
+	Hs
		516416 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Hs
		516651 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	Rn
		600488 PABP1_RAT (1-267): 1.05e-37: 142: 13.77		MK03_RAT (75-267): 1.43e-44: 164: 20.90
+	Rn
		102586 G3V9N0_RAT (1-270): 2.87e-37: 141: 14.34		MK03_RAT (75-267): 1.43e-44: 164: 20.90
+	Hs
		834037 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		833731 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		CLK1_HUMAN (405-566): 8.71e-11: 66.2: 26.01
+	Dm
		580161 TRA2_DROME (97-281): 1.36e-44: 153: 43.78		DOA_DROME (396-566): 7.94e-12: 70.1: 25.41
+	Hs
		516417 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		834033 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		833706 TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30		CLK1_HUMAN (405-566): 8.71e-11: 66.2: 26.01