HitPredict

Interactor 1: SNX1 (Q13596)
Sorting nexin-1
Gene: SNX1

Interactor 2: STAM1 (Q92783)
Signal transducing adapter molecule 1 (STAM-1)
Gene: STAM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031901 - early endosome membrane GO:0035091 - phosphatidylinositol binding GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 522 Hs			1 540
+	Hs
		159992 SNX1_HUMAN (1-522): 8.2e-149: 438: 100.00		HGS_HUMAN (84-540): 8.62e-15: 79.4: 13.50
+	Hs
		241210 SNX5_HUMAN (142-520): 9.13e-75: 243: 21.45		TOM1_HUMAN (6-454): 3.66e-69: 232: 16.81
+	Hs
		275222 SNX18_HUMAN (7-477): 5.44e-96: 305: 18.15		GRAP2_HUMAN (213-264): 2.75e-14: 75.9: 57.69
+	Hs
		924801 SNX18_HUMAN (7-477): 5.44e-96: 305: 18.15		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Mm
		1141156 SNX18_MOUSE (7-521): 1.07e-95: 304: 16.48		GRB2_MOUSE (215-265): 2.65e-13: 71.2: 54.90
+	Hs
		160232 SNX7_HUMAN (114-515): 3.23e-86: 273: 19.65		HGS_HUMAN (84-540): 8.62e-15: 79.4: 13.50
+	Hs
		924952 SNX7_HUMAN (114-515): 3.23e-86: 273: 19.65		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Hs
		160244 SNX5_HUMAN (142-520): 9.13e-75: 243: 21.45		HGS_HUMAN (84-540): 8.62e-15: 79.4: 13.50
+	Hs
		924951 SNX12_HUMAN (106-272): 2.12e-46: 161: 27.55		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Hs
		234938 SNX3_HUMAN (118-273): 6.27e-46: 160: 24.36		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90