HitPredict

Interactor 1: PWP1 (Q13610)
Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502)
Gene: PWP1

Interactor 2: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17079684
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 501 Hs			1 1140
+	Hs
		1082263 WDR5B_HUMAN (28-370): 4.44e-55: 189: 12.68		DDB1_HUMAN (1-1140): 0: 1424: 100.00
+	Hs
		245605 TBL1X_HUMAN (26-374): 1.02e-50: 183: 15.10		DDB1_HUMAN (1-1140): 0: 1424: 100.00
+	Hs
		1082327 SNR40_HUMAN (16-369): 1.71e-44: 162: 14.88		DDB1_HUMAN (1-1140): 0: 1424: 100.00
+	Hs
		1082374 TBL1R_HUMAN (7-331): 4.59e-39: 150: 14.89		DDB1_HUMAN (1-1140): 0: 1424: 100.00
+	Hs
		921580 GBB2_HUMAN (247-492): 1.81e-36: 139: 15.75		DDB1_HUMAN (1-1140): 0: 1424: 100.00
+	Hs
		903254 WDR5_HUMAN (7-223): 2.82e-12: 69.6: 10.08		DDB1_HUMAN (1-1140): 0: 1424: 100.00
+	At
		1274999 Q93VK1_ARATH (202-475): 1.26e-56: 196: 18.91		DDB1A_ARATH (2-1140): 0: 1255: 52.09
+	Hs
		1073094 FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09		SF3B3_HUMAN (3-1126): 0: 1102: 21.33
+	At
		1258990 Q8W4D9_ARATH (275-458): 4.52e-11: 66.6: 25.40		DDB1A_ARATH (2-1140): 0: 1255: 52.09
+	At
		1340748 HTD1_ARATH (254-415): 1.65e-10: 65.1: 27.33		DDB1A_ARATH (2-1140): 0: 1255: 52.09
+	At
		186951 MSI3_ARATH (253-415): 3.64e-10: 63.9: 24.59		DDB1A_ARATH (2-1140): 0: 1255: 52.09
+	At
		186950 MSI3_ARATH (253-415): 3.64e-10: 63.9: 24.59		DDB1B_ARATH (3-1140): 0: 1248: 50.92
+	Hs
		1073168 NLE1_HUMAN (37-167): 4.93e-11: 66.9: 10.69		SF3B3_HUMAN (3-1126): 0: 1102: 21.33
+	Sc
		744701 TAF5_YEAST (38-477): 1.32e-71: 244: 17.13		CFT1_YEAST (11-1125): 0: 678: 14.79
+	Hs
		1014128 TAF5_HUMAN (66-363): 3.47e-40: 156: 15.95		CPSF1_HUMAN (4-527): 4.39e-117: 397: 15.87
+	Hs
		1014208 NLE1_HUMAN (37-167): 4.93e-11: 66.9: 10.69		CPSF1_HUMAN (4-527): 4.39e-117: 397: 15.87