HitPredict

Interactor 1: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (p62)
Gene: SQSTM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

The method score is based on:

Property	Details
Experiments	34079125, 28734243, 23333919
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0002931 - response to ischemia GO:0005783 - endoplasmic reticulum GO:0008104 - intracellular protein localization GO:0019899 - enzyme binding and 6 others more... GO:0019901 - protein kinase binding GO:0030154 - cell differentiation GO:0030674 - protein-macromolecule adaptor activity GO:0031397 - negative regulation of protein ubiquitination GO:0044877 - protein-containing complex binding GO:0140311 - protein sequestering activity
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	178
Hs

1	440

Service provided by Combinatics, Japan

Last updated: 11Aug2025