HitPredict

Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Interactor 2: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 776 Hs			1 1374
+	Hs
		1043526 CUL4B_HUMAN (7-776): 0: 773: 29.90		LMTK3_HUMAN (7-1342): 9.67e-159: 518: 29.10
+	Hs
		609280 CUL4B_HUMAN (7-776): 0: 773: 29.90		FGFR3_HUMAN (29-448): 5.82e-123: 403: 23.42
+	Hs
		411713 CUL3_HUMAN (9-776): 0: 748: 30.47		LCK_HUMAN (98-410): 1.51e-107: 352: 24.20
+	Hs
		384802 CUL1_HUMAN (1-776): 0: 911: 100.00		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384805 CUL4B_HUMAN (7-776): 0: 773: 29.90		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		411381 CUL3_HUMAN (9-776): 0: 748: 30.47		INSR_HUMAN (111-395): 4.12e-41: 167: 36.27
+	Rn
		78187 CUL3_RAT (9-776): 0: 748: 30.35		INSR_RAT (111-395): 8.57e-39: 160: 35.25
+	Hs
		435637 CUL3_HUMAN (9-776): 0: 748: 30.47		IGF1R_HUMAN (119-391): 2.65e-38: 159: 34.51
+	Hs
		1041683 CUL3_HUMAN (9-776): 0: 748: 30.47		DDR2_HUMAN (108-395): 1.06e-36: 152: 33.86
+	Hs
		384804 CUL3_HUMAN (9-776): 0: 748: 30.47		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384803 CUL2_HUMAN (13-776): 0: 720: 35.98		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		337467 CUL4A_HUMAN (7-776): 0: 781: 30.41		ABL1_HUMAN (588-1118): 4.91e-10: 66.4: 13.32
+	Hs
		337468 CUL4B_HUMAN (7-776): 0: 773: 29.90		ABL1_HUMAN (588-1118): 4.91e-10: 66.4: 13.32
+	Hs
		385301 CUL5_HUMAN (2-776): 0: 622: 28.85		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77