HitPredict

Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Interactor 2: FBX25 (Q8TCJ0)
F-box only protein 25
Gene: FBXO25

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	37028429, 20473970, 16278047, 16714087
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination GO:0019005 - SCF ubiquitin ligase complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 776 Hs			1 367
+	Hs
		1041135 CUL1_HUMAN (1-776): 0: 911: 100.00		FBX32_HUMAN (1-367): 8.84e-180: 504: 59.89
+	Mm
		1321639 CUL1_MOUSE (1-776): 0: 912: 99.87		FBX32_MOUSE (1-367): 4.23e-174: 490: 58.27
+	Hs
		1043148 CUL4A_HUMAN (7-776): 0: 781: 30.41		FBX32_HUMAN (1-367): 8.84e-180: 504: 59.89
+	Hs
		1043500 CUL4B_HUMAN (7-776): 0: 773: 29.90		FBX32_HUMAN (1-367): 8.84e-180: 504: 59.89