Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.990

The method score is based on:

Property Details
Experiments 25144743, 22956996, 19141280, 22959436, 26265931, 24973710, 27774986, 31950832, 36037385, 37028429, 19615732, 16036220, 22767593, 22013077, 21145461, 29103612, 29863914, 34237211, 36423380, 21249194 and 3 others

more...

Identification Methods enzymatic study, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin_Nedd8~JAB
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 776
Hs

1 334
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Last updated: 15 Jul 2024