Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1
Interactor 2: FBXW5 (Q969U6)
F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5)
Gene: FBXW5
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.93 | 1.00 | 0.968 |
The method score is based on:
Property | Details |
---|---|
Experiments | 29103612, 37028429, 21145461, 25143387, 25515538, 35813202, 14603323, 23319600, 23314863 |
Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, coimmunoprecipitation |
Interaction Type | physical association, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Cullin~F-box-like |
Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0019005 - SCF ubiquitin ligase complex GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and 1 others more... |
Homologous interactions | 4 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024