Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Interactor 2: FBX17 (Q96EF6)
F-box only protein 17 (F-box only protein 26)
Gene: FBXO17

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 18203720, 29103612, 37028429, 21145461
Identification Methods affinity chromatography technology, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~F-box-like
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019005 - SCF ubiquitin ligase complex
GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 776
Hs

1 278
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024