Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Interactor 2: FXL18 (Q96ME1)
F-box/LRR-repeat protein 18 (F-box and leucine-rich repeat protein 18)
Gene: FBXL18

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.90 0.811

The method score is based on:

Property Details
Experiments 29103612, 37028429, 21145461
Identification Methods affinity chromatography technology, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~F-box-like
Common GO terms GO:0005829 - cytosol
GO:0019005 - SCF ubiquitin ligase complex
GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions 0

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Last updated: 15 Jul 2024