Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Interactor 2: FBX3 (Q9UK99)
F-box only protein 3
Gene: FBXO3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.963

The method score is based on:

Property Details
Experiments 29103612, 37028429, 21145461, 32891887, 33961781, 36044955, 18809579
Identification Methods affinity chromatography technology, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~F-box-like
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0019005 - SCF ubiquitin ligase complex
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 776
Hs

1 471
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024