HitPredict

Interactor 1: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Interactor 2: LRC14 (Q15048)
Leucine-rich repeat-containing protein 14
Gene: LRRC14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.671

Property	Details
Experiments	33961781, 21145461, 19295130
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 493
+	Hs
		316225 CUL2_HUMAN (1-745): 0: 840: 100.00		PRA12_HUMAN (3-482): 1.31e-178: 511: 26.20
+	Hs
		824 CUL2_HUMAN (1-745): 0: 840: 100.00		A0A096LNW4_HUMAN (3-480): 1.74e-175: 503: 28.39
+	Hs
		1041358 CUL2_HUMAN (1-745): 0: 840: 100.00		PRA17_HUMAN (3-482): 5.12e-174: 499: 22.45
+	Hs
		241238 CUL2_HUMAN (1-745): 0: 840: 100.00		PRAM2_HUMAN (3-481): 5.3e-160: 463: 24.27
+	Hs
		943713 CUL2_HUMAN (1-745): 0: 840: 100.00		PRAME_HUMAN (2-480): 2.51e-156: 455: 29.86
+	Hs
		1041151 CUL1_HUMAN (6-745): 0: 775: 36.24		NLRP3_HUMAN (194-374): 9.53e-09: 60.1: 20.62
+	Hs
		1043169 CUL4A_HUMAN (4-745): 0: 773: 26.86		NLRP3_HUMAN (194-374): 9.53e-09: 60.1: 20.62
+	Hs
		1043523 CUL4B_HUMAN (4-745): 0: 771: 27.79		NLRP3_HUMAN (194-374): 9.53e-09: 60.1: 20.62
+	Hs
		1042319 CUL3_HUMAN (1-745): 0: 768: 26.38		NLRP3_HUMAN (194-374): 9.53e-09: 60.1: 20.62