HitPredict

Interactor 1: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 745 Hs			1 471
+	Hs
		1031316 CUL2_HUMAN (1-745): 0: 840: 100.00		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		1043359 CUL4B_HUMAN (4-745): 0: 771: 27.79		NONO_HUMAN (1-471): 1.15e-97: 303: 100.00
+	Hs
		516504 CUL2_HUMAN (1-745): 0: 840: 100.00		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		1031315 CUL1_HUMAN (6-745): 0: 775: 36.24		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		1031318 CUL4A_HUMAN (4-745): 0: 773: 26.86		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		1031319 CUL4B_HUMAN (4-745): 0: 771: 27.79		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		1041335 CUL2_HUMAN (1-745): 0: 840: 100.00		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		1043481 CUL4B_HUMAN (4-745): 0: 771: 27.79		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		516503 CUL1_HUMAN (6-745): 0: 775: 36.24		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		516506 CUL4A_HUMAN (4-745): 0: 773: 26.86		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		516507 CUL4B_HUMAN (4-745): 0: 771: 27.79		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		516505 CUL3_HUMAN (1-745): 0: 768: 26.38		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		613446 CUL4B_HUMAN (4-745): 0: 771: 27.79		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		613445 CUL3_HUMAN (1-745): 0: 768: 26.38		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		1041002 CUL1_HUMAN (6-745): 0: 775: 36.24		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		1043367 CUL4B_HUMAN (4-745): 0: 771: 27.79		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		1041459 CUL2_HUMAN (1-745): 0: 840: 100.00		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71
+	Hs
		1020253 CUL3_HUMAN (1-745): 0: 768: 26.38		ELAV2_HUMAN (150-210): 9.69e-14: 74.5: 25.81
+	Hs
		1041183 CUL1_HUMAN (6-745): 0: 775: 36.24		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71
+	Hs
		1043557 CUL4B_HUMAN (4-745): 0: 771: 27.79		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71