Interactor 1: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Interactor 2: ELOB (Q15370)
Elongin-B (EloB) (Elongin 18 kDa subunit) (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Transcription elongation factor B polypeptide 2)
Gene: ELOB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 31253590, 24981860, 12048197, 30166453, 11384984, 18173839, 15966899, 12149480, 21145461, 9122164, 15601820, 24076655, 19327355
Identification Methods affinity chromatography technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~ubiquitin, Cullin_Nedd8~ubiquitin
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0030891 - VCB complex
GO:0031462 - Cul2-RING ubiquitin ligase complex
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 745
Hs

1 118
+ Hs
+ Hs
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024