HitPredict

Interactor 1: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Interactor 2: HNRL1 (Q9BUJ2)
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5)
Gene: HNRNPUL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 745 Hs			1 856
+	Hs
		1041181 CUL1_HUMAN (6-745): 0: 775: 36.24		HNRL1_HUMAN (1-856): 0: 768: 100.00
+	Hs
		1043199 CUL4A_HUMAN (4-745): 0: 773: 26.86		HNRL1_HUMAN (1-856): 0: 768: 100.00
+	Hs
		1043552 CUL4B_HUMAN (4-745): 0: 771: 27.79		HNRL1_HUMAN (1-856): 0: 768: 100.00
+	Hs
		1042433 CUL3_HUMAN (1-745): 0: 768: 26.38		HNRL1_HUMAN (1-856): 0: 768: 100.00
+	Hs
		962067 CUL2_HUMAN (1-745): 0: 840: 100.00		HNRPU_HUMAN (1-701): 0: 662: 40.41
+	Hs
		962066 CUL1_HUMAN (6-745): 0: 775: 36.24		HNRPU_HUMAN (1-701): 0: 662: 40.41
+	Mm
		1257577 CUL3_MOUSE (1-745): 0: 768: 26.50		HNRPU_MOUSE (1-701): 0: 664: 41.47
+	Hs
		962068 CUL3_HUMAN (1-745): 0: 768: 26.38		HNRPU_HUMAN (1-701): 0: 662: 40.41
+	Hs
		1041686 CUL3_HUMAN (1-745): 0: 768: 26.38		HNRL2_HUMAN (1-707): 0: 587: 38.67
+	Hs
		1041414 CUL2_HUMAN (1-745): 0: 840: 100.00		DDX1_HUMAN (141-512): 9.29e-85: 288: 21.91
+	Hs
		1040996 CUL1_HUMAN (6-745): 0: 775: 36.24		RYR3_HUMAN (115-499): 1.45e-81: 290: 14.22
+	Hs
		1041118 CUL1_HUMAN (6-745): 0: 775: 36.24		DDX1_HUMAN (141-512): 9.29e-85: 288: 21.91
+	Hs
		1043129 CUL4A_HUMAN (4-745): 0: 773: 26.86		DDX1_HUMAN (141-512): 9.29e-85: 288: 21.91
+	Hs
		1043484 CUL4B_HUMAN (4-745): 0: 771: 27.79		DDX1_HUMAN (141-512): 9.29e-85: 288: 21.91
+	Hs
		1042169 CUL3_HUMAN (1-745): 0: 768: 26.38		DDX1_HUMAN (141-512): 9.29e-85: 288: 21.91
+	Hs
		1042737 CUL3_HUMAN (1-745): 0: 768: 26.38		ASH2L_HUMAN (25-410): 6.7e-69: 242: 16.20
+	Hs
		1042345 CUL3_HUMAN (1-745): 0: 768: 26.38		RANB9_HUMAN (142-503): 1.14e-67: 241: 18.90
+	Hs
		1043069 CUL4A_HUMAN (4-745): 0: 773: 26.86		RBP10_HUMAN (146-503): 3.04e-61: 220: 16.80
+	Hs
		1041863 CUL3_HUMAN (1-745): 0: 768: 26.38		RBP10_HUMAN (146-503): 3.04e-61: 220: 16.80
+	Hs
		1041782 CUL3_HUMAN (1-745): 0: 768: 26.38		RN123_HUMAN (243-412): 6.53e-44: 174: 26.86