HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: ZMYM4 (Q5VZL5)
Zinc finger MYM-type protein 4 (Zinc finger protein 262)
Gene: ZMYM4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 1548
+	Hs
		1042749 CUL3_HUMAN (1-768): 0: 951: 100.00		ZMYM2_HUMAN (60-1543): 0: 1059: 32.28
+	Hs
		1041557 CUL3_HUMAN (1-768): 0: 951: 100.00		ZMYM3_HUMAN (164-1543): 0: 1039: 31.74
+	Hs
		1041826 CUL3_HUMAN (1-768): 0: 951: 100.00		Z585A_HUMAN (288-947): 1.37e-172: 539: 12.26
+	Hs
		67426 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN850_HUMAN (153-809): 7.11e-167: 534: 11.17
+	Hs
		983757 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF91_HUMAN (136-709): 2.32e-132: 443: 13.24
+	Hs
		846676 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF84_HUMAN (414-958): 1.23e-127: 417: 11.47
+	Hs
		1041764 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN658_HUMAN (162-957): 1.97e-117: 398: 10.73
+	Hs
		1041958 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN761_HUMAN (500-946): 6.99e-107: 360: 10.27
+	Hs
		1041966 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN573_HUMAN (544-949): 6.18e-100: 337: 9.68
+	Hs
		1042724 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN624_HUMAN (572-961): 7.7e-92: 320: 11.26
+	Hs
		1042045 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN615_HUMAN (568-958): 1.38e-81: 287: 10.35
+	Hs
		1041578 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN268_HUMAN (216-554): 3.7e-73: 267: 12.53
+	Hs
		1041738 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN569_HUMAN (580-946): 1.46e-64: 235: 9.48
+	Hs
		1042028 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN808_HUMAN (157-511): 4.17e-51: 198: 14.10
+	Hs
		1041745 CUL3_HUMAN (1-768): 0: 951: 100.00		ZMYM1_HUMAN (605-941): 2.11e-48: 191: 19.10
+	Hs
		1042371 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN184_HUMAN (705-947): 7.62e-41: 165: 9.70
+	Hs
		1042010 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN567_HUMAN (365-709): 2.77e-27: 121: 14.98
+	Hs
		1042690 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN226_HUMAN (145-435): 3.63e-24: 112: 9.75
+	Hs
		1041579 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN234_HUMAN (157-423): 2.18e-19: 96.8: 10.15
+	Hs
		73014 CUL3_HUMAN (1-768): 0: 951: 100.00		B4DU56_HUMAN (340-594): 1e-13: 78.1: 15.39