HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: EDC4 (Q6P2E9)
Enhancer of mRNA-decapping protein 4 (Autoantigen Ge-1) (Autoantigen RCD-8) (Human enhancer of decapping large subunit) (Hedls)
Gene: EDC4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 1401
+	Hs
		1042847 CUL3_HUMAN (1-768): 0: 951: 100.00		MACF1_HUMAN (908-1276): 1.45e-46: 186: 10.59
+	Hs
		1042290 CUL3_HUMAN (1-768): 0: 951: 100.00		CHAP1_HUMAN (435-998): 6.58e-12: 72.5: 9.91
+	Hs
		1042076 CUL3_HUMAN (1-768): 0: 951: 100.00		KMT2C_HUMAN (433-1018): 2.98e-10: 67.5: 10.44
+	Hs
		1042196 CUL3_HUMAN (1-768): 0: 951: 100.00		CBP_HUMAN (423-883): 7.13e-10: 66.3: 11.91
+	Hs
		577634 CUL3_HUMAN (1-768): 0: 951: 100.00		SON_HUMAN (426-1085): 5.29e-09: 63.2: 11.38