HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: LRC8B (Q6P9F7)
Volume-regulated anion channel subunit LRRC8B (Leucine-rich repeat-containing protein 8B) (T-cell activation leucine repeat-rich protein) (TA-LRRP)
Gene: LRRC8B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25011449
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 803
+	Hs
		1041876 CUL3_HUMAN (1-768): 0: 951: 100.00		PHLP2_HUMAN (343-757): 1.51e-39: 160: 19.65
+	Hs
		1041552 CUL3_HUMAN (1-768): 0: 951: 100.00		SCRIB_HUMAN (350-644): 1.76e-38: 157: 21.45
+	Hs
		1042425 CUL3_HUMAN (1-768): 0: 951: 100.00		LRRC1_HUMAN (342-619): 2.47e-22: 103: 17.63
+	Hs
		1042318 CUL3_HUMAN (1-768): 0: 951: 100.00		LRRC7_HUMAN (328-480): 1.69e-21: 102: 16.77
+	Hs
		1042341 CUL3_HUMAN (1-768): 0: 951: 100.00		ERBIN_HUMAN (328-480): 5.16e-21: 101: 16.77
+	Hs
		1041636 CUL3_HUMAN (1-768): 0: 951: 100.00		RSU1_HUMAN (609-797): 7.72e-18: 86.3: 29.44
+	Hs
		1023157 CUL3_HUMAN (1-768): 0: 951: 100.00		FLII_HUMAN (430-718): 4.47e-16: 85.1: 25.71
+	Hs
		1043528 CUL4B_HUMAN (5-768): 0: 779: 36.77		ERBIN_HUMAN (328-480): 5.16e-21: 101: 16.77
+	Hs
		1043003 CUL4A_HUMAN (10-768): 0: 791: 38.32		RSU1_HUMAN (609-797): 7.72e-18: 86.3: 29.44