HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: KCTD1 (Q719H9)
BTB/POZ domain-containing protein KCTD1 (Potassium channel tetramerization domain-containing protein 1)
Gene: KCTD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	30190310
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 257
+	Hs
		1042523 CUL3_HUMAN (1-768): 0: 951: 100.00		BACD3_HUMAN (1-225): 4.22e-58: 189: 20.25
+	Hs
		1042165 CUL3_HUMAN (1-768): 0: 951: 100.00		BACD1_HUMAN (10-225): 4.1e-53: 176: 18.14
+	Hs
		1041533 CUL3_HUMAN (1-768): 0: 951: 100.00		BACD2_HUMAN (9-225): 2.64e-52: 174: 18.50
+	Hs
		1042242 CUL3_HUMAN (1-768): 0: 951: 100.00		KCD12_HUMAN (23-243): 7.97e-52: 173: 23.43
+	Hs
		1042675 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD5_HUMAN (7-179): 1.39e-45: 154: 21.47
+	Hs
		1042309 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD7_HUMAN (9-165): 3.02e-43: 149: 27.85
+	Hs
		1041705 CUL3_HUMAN (1-768): 0: 951: 100.00		KCD21_HUMAN (29-130): 4.69e-42: 145: 47.06
+	Hs
		1042035 CUL3_HUMAN (1-768): 0: 951: 100.00		KCD17_HUMAN (30-153): 5.03e-40: 142: 25.81
+	Hs
		1041584 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD2_HUMAN (4-153): 2.22e-40: 141: 25.95
+	Hs
		1042063 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD6_HUMAN (29-126): 9.59e-39: 136: 50.00
+	Hs
		1041790 CUL3_HUMAN (1-768): 0: 951: 100.00		KCD11_HUMAN (55-156): 3.2e-26: 103: 29.52
+	Hs
		1042934 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD3_HUMAN (22-143): 1.05e-22: 98.6: 28.68
+	Hs
		1041839 CUL3_HUMAN (1-768): 0: 951: 100.00		KCD18_HUMAN (24-118): 2.21e-22: 97.1: 30.53
+	Dm
		1213854 Q8IP45_DROME (17-768): 0: 868: 69.08		Q9W579_DROME (14-134): 2.92e-40: 139: 24.59
+	Ce
		1088887 CUL3_CAEEL (4-768): 0: 792: 48.08		Q965M5_CAEEL (25-237): 1.17e-55: 179: 19.27
+	Ce
		1088878 CUL3_CAEEL (4-768): 0: 792: 48.08		Q18776_CAEEL (1-178): 4.23e-46: 156: 21.98
+	Ce
		954547 CUL3_CAEEL (4-768): 0: 792: 48.08		P91563_CAEEL (29-176): 1.58e-44: 151: 20.95
+	Ce
		1088879 CUL3_CAEEL (4-768): 0: 792: 48.08		Q18986_CAEEL (27-170): 8.52e-44: 149: 25.69
+	Ce
		184054 CUL3_CAEEL (4-768): 0: 792: 48.08		O16612_CAEEL (27-164): 1.96e-23: 95.9: 25.36
+	Ce
		109385 CUL3_CAEEL (4-768): 0: 792: 48.08		H2KY83_CAEEL (27-164): 1.58e-23: 95.5: 25.36