HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: KAISO (Q86T24)
Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33)
Gene: ZBTB33

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane and 1 others more... GO:0016055 - Wnt signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 672
+	Hs
		67426 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN850_HUMAN (198-672): 5.58e-104: 342: 14.49
+	Hs
		983757 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF91_HUMAN (240-672): 9.2e-100: 333: 14.07
+	Hs
		988832 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN33B_HUMAN (83-423): 8.49e-79: 268: 8.07
+	Hs
		1041696 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN829_HUMAN (396-596): 3.18e-68: 231: 19.91
+	Hs
		970659 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF45_HUMAN (111-464): 3.66e-59: 212: 7.63
+	Hs
		1041578 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN268_HUMAN (83-304): 2.79e-41: 163: 6.22
+	Hs
		73009 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN879_HUMAN (169-516): 7.59e-42: 161: 8.26
+	Hs
		565092 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF7_HUMAN (103-418): 8.75e-41: 160: 6.27
+	Hs
		73014 CUL3_HUMAN (1-768): 0: 951: 100.00		B4DU56_HUMAN (109-305): 1.96e-40: 158: 6.50
+	Hs
		846676 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF84_HUMAN (109-276): 2.41e-37: 150: 9.36
+	Hs
		1041579 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN234_HUMAN (109-269): 4.16e-29: 125: 8.54
+	Hs
		1024288 CUL3_HUMAN (1-768): 0: 951: 100.00		ZBT17_HUMAN (109-353): 3.01e-25: 113: 6.05
+	Hs
		1041657 CUL3_HUMAN (1-768): 0: 951: 100.00		ZKSC8_HUMAN (315-451): 5.88e-18: 89.9: 10.00
+	Hs
		1041728 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN805_HUMAN (348-476): 2.78e-16: 84.5: 7.80
+	Hs
		200252 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN264_HUMAN (348-476): 2.31e-15: 81.8: 8.33
+	Hs
		1041577 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN267_HUMAN (490-606): 3.02e-09: 62.4: 29.66
+	Hs
		1041660 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF77_HUMAN (490-577): 4.33e-09: 61.6: 35.17
+	Hs
		563262 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF14_HUMAN (490-589): 6.01e-09: 61.2: 33.00
+	Hs
		215889 CUL3_HUMAN (1-768): 0: 951: 100.00		ZBT14_HUMAN (494-575): 6.13e-09: 60.8: 31.71
+	Hs
		855884 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN140_HUMAN (490-568): 6.41e-09: 60.8: 31.65