HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: ZN444 (Q8N0Y2)
Zinc finger protein 444 (Endothelial zinc finger protein 2) (EZF-2) (Zinc finger and SCAN domain-containing protein 17)
Gene: ZNF444

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 35563538
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 327
+	Hs
		565092 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF7_HUMAN (4-302): 8.27e-130: 387: 16.80
+	Hs
		1041813 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN544_HUMAN (74-321): 7.33e-82: 263: 16.04
+	Hs
		563602 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF24_HUMAN (100-248): 3.67e-36: 135: 19.14
+	Hs
		1041657 CUL3_HUMAN (1-768): 0: 951: 100.00		ZKSC8_HUMAN (10-153): 7.37e-34: 132: 37.67
+	Hs
		1041738 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN569_HUMAN (4-144): 1.68e-31: 126: 12.25
+	Hs
		563708 CUL3_HUMAN (1-768): 0: 951: 100.00		ZKSC1_HUMAN (9-178): 7.14e-32: 126: 34.71
+	Hs
		1041677 CUL3_HUMAN (1-768): 0: 951: 100.00		ZSC26_HUMAN (78-233): 1.17e-31: 125: 19.23
+	Hs
		1041728 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN805_HUMAN (231-322): 5.45e-27: 113: 23.71
+	Hs
		200252 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN264_HUMAN (247-322): 5.19e-26: 110: 32.90
+	Hs
		970659 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF45_HUMAN (217-323): 1.46e-18: 88.2: 25.23
+	Hs
		1041577 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN267_HUMAN (183-300): 1.67e-16: 82: 35.00
+	Hs
		1041580 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN460_HUMAN (181-304): 7.06e-15: 77: 33.87
+	Hs
		73009 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN879_HUMAN (273-322): 2.41e-14: 75.5: 20.00
+	Hs
		988832 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN33B_HUMAN (181-278): 2.57e-14: 75.5: 37.76
+	Hs
		563761 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN37A_HUMAN (181-277): 3.94e-13: 72: 37.11
+	Hs
		1041610 CUL3_HUMAN (1-768): 0: 951: 100.00		OZF_HUMAN (181-273): 4.87e-13: 70.5: 38.71
+	Hs
		549161 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN250_HUMAN (4-56): 2.1e-12: 69.7: 17.86
+	Hs
		846676 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF84_HUMAN (4-59): 1.17e-11: 67.4: 10.17
+	Hs
		988826 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN33A_HUMAN (205-300): 1.36e-11: 67.4: 37.37
+	Hs
		563252 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF12_HUMAN (204-300): 2.15e-10: 63.5: 31.13