HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: RUFY2 (Q8WXA3)
RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related)
Gene: RUFY2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 606
+	Hs
		1042352 CUL3_HUMAN (1-768): 0: 951: 100.00		RUFY1_HUMAN (2-603): 9.52e-53: 194: 62.46
+	Hs
		1041889 CUL3_HUMAN (1-768): 0: 951: 100.00		RUFY3_HUMAN (7-421): 4.21e-40: 154: 60.72
+	Hs
		1040929 CUL3_HUMAN (1-768): 0: 951: 100.00		MTMR3_HUMAN (377-603): 7.06e-26: 115: 20.25
+	Hs
		1042682 CUL3_HUMAN (1-768): 0: 951: 100.00		MTMR4_HUMAN (451-597): 8.19e-26: 115: 24.67
+	Hs
		313535 CUL3_HUMAN (1-768): 0: 951: 100.00		ZFYV9_HUMAN (535-602): 5.09e-22: 103: 39.13
+	Hs
		1041611 CUL3_HUMAN (1-768): 0: 951: 100.00		EEA1_HUMAN (47-561): 6.28e-20: 96.8: 12.67
+	Hs
		725157 CUL3_HUMAN (1-768): 0: 951: 100.00		MYH10_HUMAN (205-561): 4.25e-19: 94.1: 16.25
+	Hs
		724816 CUL3_HUMAN (1-768): 0: 951: 100.00		MYH9_HUMAN (205-564): 8.35e-19: 93.3: 16.67
+	Hs
		1042944 CUL3_HUMAN (1-768): 0: 951: 100.00		MRCKB_HUMAN (117-458): 5.91e-16: 84.2: 12.26
+	Hs
		1042577 CUL3_HUMAN (1-768): 0: 951: 100.00		ZFYV1_HUMAN (537-594): 2.48e-10: 65.5: 42.62
+	Hs
		1042182 CUL3_HUMAN (1-768): 0: 951: 100.00		MY18A_HUMAN (2-263): 2.8e-09: 62.5: 11.19
+	Hs
		725158 CUL4A_HUMAN (10-768): 0: 791: 38.32		MYH10_HUMAN (205-561): 4.25e-19: 94.1: 16.25
+	Hs
		1043039 CUL4A_HUMAN (10-768): 0: 791: 38.32		FKB15_HUMAN (122-497): 1.68e-13: 76.1: 12.73
+	Hs
		1043236 CUL4A_HUMAN (10-768): 0: 791: 38.32		ZFYV1_HUMAN (537-594): 2.48e-10: 65.5: 42.62
+	Hs
		1043487 CUL4B_HUMAN (5-768): 0: 779: 36.77		MY18A_HUMAN (2-263): 2.8e-09: 62.5: 11.19
+	Hs
		725156 CUL1_HUMAN (18-768): 0: 707: 30.57		MYH10_HUMAN (205-561): 4.25e-19: 94.1: 16.25
+	Hs
		724815 CUL1_HUMAN (18-768): 0: 707: 30.57		MYH9_HUMAN (205-564): 8.35e-19: 93.3: 16.67
+	Hs
		1041482 CUL2_HUMAN (30-768): 0: 672: 26.17		MTMR4_HUMAN (451-597): 8.19e-26: 115: 24.67
+	Hs
		502913 CUL1_HUMAN (18-768): 0: 707: 30.57		MYH3_HUMAN (214-561): 7.38e-14: 77.5: 11.55