HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: TITIN (Q8WZ42)
Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)
Gene: TTN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 34350
+	Hs
		1043127 CUL4A_HUMAN (10-768): 0: 791: 38.32		TITIN_HUMAN (1-34350): 0: 28064: 100.00
+	Hs
		1043482 CUL4B_HUMAN (5-768): 0: 779: 36.77		TITIN_HUMAN (1-34350): 0: 28064: 100.00
+	Hs
		1041413 CUL2_HUMAN (30-768): 0: 672: 26.17		TITIN_HUMAN (1-34350): 0: 28064: 100.00
+	Hs
		957538 CUL3_HUMAN (1-768): 0: 951: 100.00		PGBM_HUMAN (1-473): 2.15e-57: 228: 19.30
+	Hs
		1042342 CUL3_HUMAN (1-768): 0: 951: 100.00		HMCN1_HUMAN (33994-34347): 3.18e-40: 171: 18.08
+	Hs
		957539 CUL4A_HUMAN (10-768): 0: 791: 38.32		PGBM_HUMAN (1-473): 2.15e-57: 228: 19.30
+	Hs
		1043046 CUL4A_HUMAN (10-768): 0: 791: 38.32		OBSCN_HUMAN (30666-30849): 2.08e-16: 92.7: 24.32
+	Hs
		1042987 CUL4A_HUMAN (10-768): 0: 791: 38.32		MYPC3_HUMAN (6822-7413): 2.5e-09: 68.9: 23.12
+	Hs
		1040985 CUL1_HUMAN (18-768): 0: 707: 30.57		MYPC3_HUMAN (6822-7413): 2.5e-09: 68.9: 23.12