HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: SMRC1 (Q92922)
SWI/SNF complex subunit SMARCC1 (BRG1-associated factor 155) (BAF155) (SWI/SNF complex 155 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1)
Gene: SMARCC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 1105
+	Hs
		1043494 CUL4B_HUMAN (5-768): 0: 779: 36.77		SMRC1_HUMAN (30-1074): 0: 1148: 100.00
+	Hs
		1042092 CUL3_HUMAN (1-768): 0: 951: 100.00		SMRC2_HUMAN (32-1105): 0: 956: 57.71
+	Hs
		1043466 CUL4B_HUMAN (5-768): 0: 779: 36.77		SMRC2_HUMAN (32-1105): 0: 956: 57.71
+	Hs
		998679 CUL3_HUMAN (1-768): 0: 951: 100.00		EP300_HUMAN (769-1082): 7e-28: 124: 13.19
+	Hs
		1042076 CUL3_HUMAN (1-768): 0: 951: 100.00		KMT2C_HUMAN (664-1105): 1.43e-09: 65: 7.64
+	Hs
		261503 CUL4B_HUMAN (5-768): 0: 779: 36.77		NCOR1_HUMAN (619-1062): 6.7e-30: 131: 11.55
+	Hs
		998680 CUL4B_HUMAN (5-768): 0: 779: 36.77		EP300_HUMAN (769-1082): 7e-28: 124: 13.19
+	Hs
		998678 CUL1_HUMAN (18-768): 0: 707: 30.57		EP300_HUMAN (769-1082): 7e-28: 124: 13.19