HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: FUBP2 (Q92945)
Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75)
Gene: KHSRP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	27899653, 35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 711
+	Hs
		1042231 CUL3_HUMAN (1-768): 0: 951: 100.00		FUBP1_HUMAN (70-707): 2.96e-89: 294: 58.65
+	Hs
		1043495 CUL4B_HUMAN (5-768): 0: 779: 36.77		FUBP2_HUMAN (1-689): 4.89e-129: 400: 100.00
+	Hs
		1041129 CUL1_HUMAN (18-768): 0: 707: 30.57		FUBP2_HUMAN (1-689): 4.89e-129: 400: 100.00
+	Hs
		1043505 CUL4B_HUMAN (5-768): 0: 779: 36.77		FUBP1_HUMAN (70-707): 2.96e-89: 294: 58.65
+	Hs
		1041628 CUL3_HUMAN (1-768): 0: 951: 100.00		PCBP1_HUMAN (52-397): 2.33e-25: 110: 14.25
+	Hs
		128168 CUL3_HUMAN (1-768): 0: 951: 100.00		IF2B3_HUMAN (325-647): 8.75e-23: 105: 15.34
+	Hs
		1041629 CUL3_HUMAN (1-768): 0: 951: 100.00		PCBP2_HUMAN (52-400): 2.58e-22: 101: 15.28
+	Hs
		903927 CUL3_HUMAN (1-768): 0: 951: 100.00		HNRPK_HUMAN (8-210): 5.64e-11: 67.3: 20.20
+	Hs
		1042698 CUL3_HUMAN (1-768): 0: 951: 100.00		IF2B1_HUMAN (61-231): 3.23e-10: 65.5: 16.76
+	Mm
		904359 CUL3_MOUSE (1-768): 0: 949: 99.48		HNRPK_MOUSE (8-210): 5.64e-11: 67.3: 20.20
+	Hs
		1042958 CUL3_HUMAN (1-768): 0: 951: 100.00		IF2B2_HUMAN (61-211): 4.12e-10: 65.1: 20.26
+	Hs
		903928 CUL4A_HUMAN (10-768): 0: 791: 38.32		HNRPK_HUMAN (8-210): 5.64e-11: 67.3: 20.20
+	Hs
		1043266 CUL4A_HUMAN (10-768): 0: 791: 38.32		IF2B1_HUMAN (61-231): 3.23e-10: 65.5: 16.76
+	Hs
		903929 CUL4B_HUMAN (5-768): 0: 779: 36.77		HNRPK_HUMAN (8-210): 5.64e-11: 67.3: 20.20
+	Hs
		1043620 CUL4B_HUMAN (5-768): 0: 779: 36.77		IF2B1_HUMAN (61-231): 3.23e-10: 65.5: 16.76
+	Hs
		1040993 CUL1_HUMAN (18-768): 0: 707: 30.57		PCBP1_HUMAN (52-397): 2.33e-25: 110: 14.25
+	Hs
		1040994 CUL1_HUMAN (18-768): 0: 707: 30.57		PCBP2_HUMAN (52-400): 2.58e-22: 101: 15.28
+	Hs
		903925 CUL1_HUMAN (18-768): 0: 707: 30.57		HNRPK_HUMAN (8-210): 5.64e-11: 67.3: 20.20
+	Hs
		1041235 CUL1_HUMAN (18-768): 0: 707: 30.57		IF2B1_HUMAN (61-231): 3.23e-10: 65.5: 16.76
+	Hs
		903926 CUL2_HUMAN (30-768): 0: 672: 26.17		HNRPK_HUMAN (8-210): 5.64e-11: 67.3: 20.20