Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: FBXW5 (Q969U6)
F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5)
Gene: FBXW5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 25011449
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~F-box-like
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 768
Hs

1 566
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024