HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: LRC59 (Q96AG4)
Leucine-rich repeat-containing protein 59 (Ribosome-binding protein p34) (p34) [Cleaved into: Leucine-rich repeat-containing protein 59, N-terminally processed]
Gene: LRRC59

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	35563538, 37207277
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 307
+	Hs
		1041552 CUL3_HUMAN (1-768): 0: 951: 100.00		SCRIB_HUMAN (24-234): 1.09e-23: 103: 20.85
+	Hs
		1042318 CUL3_HUMAN (1-768): 0: 951: 100.00		LRRC7_HUMAN (20-124): 8.15e-18: 85.9: 28.57
+	Hs
		1042341 CUL3_HUMAN (1-768): 0: 951: 100.00		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	Hs
		1042425 CUL3_HUMAN (1-768): 0: 951: 100.00		LRRC1_HUMAN (39-128): 3.83e-12: 68.5: 26.37
+	Hs
		1041636 CUL3_HUMAN (1-768): 0: 951: 100.00		RSU1_HUMAN (9-84): 6.37e-12: 66.6: 34.21
+	Hs
		1042302 CUL3_HUMAN (1-768): 0: 951: 100.00		LLR1_HUMAN (44-121): 2.85e-09: 59.7: 44.87
+	Hs
		1043528 CUL4B_HUMAN (5-768): 0: 779: 36.77		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	Hs
		1043003 CUL4A_HUMAN (10-768): 0: 791: 38.32		RSU1_HUMAN (9-84): 6.37e-12: 66.6: 34.21
+	Hs
		1043165 CUL4A_HUMAN (10-768): 0: 791: 38.32		LLR1_HUMAN (44-121): 2.85e-09: 59.7: 44.87
+	Hs
		1041436 CUL2_HUMAN (30-768): 0: 672: 26.17		LLR1_HUMAN (44-121): 2.85e-09: 59.7: 44.87
+	Hs
		1274018 CUL5_HUMAN (25-768): 0: 597: 23.77		LLR1_HUMAN (44-121): 2.85e-09: 59.7: 44.87