HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: ZBT10 (Q96DT7)
Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF)
Gene: ZBTB10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 871
+	Hs
		1041813 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN544_HUMAN (447-870): 2.03e-97: 322: 11.01
+	Hs
		988832 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN33B_HUMAN (422-751): 7.2e-91: 306: 8.06
+	Hs
		988826 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN33A_HUMAN (422-747): 1.37e-86: 295: 8.46
+	Hs
		73009 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN879_HUMAN (432-772): 4.87e-78: 265: 9.83
+	Hs
		1041738 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN569_HUMAN (433-718): 7.66e-71: 249: 6.53
+	Hs
		1041657 CUL3_HUMAN (1-768): 0: 951: 100.00		ZKSC8_HUMAN (633-776): 6.18e-49: 184: 17.45
+	Hs
		846676 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF84_HUMAN (722-871): 1.05e-43: 171: 17.09
+	Hs
		73014 CUL3_HUMAN (1-768): 0: 951: 100.00		B4DU56_HUMAN (430-666): 2.53e-42: 166: 7.88
+	Hs
		1041579 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN234_HUMAN (372-681): 3.83e-41: 163: 9.32
+	Hs
		563252 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF12_HUMAN (435-719): 1.07e-34: 143: 6.55
+	Hs
		215889 CUL3_HUMAN (1-768): 0: 951: 100.00		ZBT14_HUMAN (724-855): 1.74e-35: 142: 23.70
+	Hs
		1041764 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN658_HUMAN (451-871): 5.16e-32: 136: 7.59
+	Hs
		1041578 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN268_HUMAN (432-613): 5.54e-28: 123: 6.04
+	Hs
		983757 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF91_HUMAN (430-575): 4.03e-16: 85.5: 6.16
+	Hs
		1024288 CUL3_HUMAN (1-768): 0: 951: 100.00		ZBT17_HUMAN (452-693): 2.71e-13: 75.9: 6.00
+	Hs
		781364 CUL3_HUMAN (1-768): 0: 951: 100.00		BCL6_HUMAN (350-460): 2.6e-13: 75.9: 41.44
+	Hs
		312064 CUL3_HUMAN (1-768): 0: 951: 100.00		ZBT7A_HUMAN (350-459): 4.45e-13: 74.7: 31.82
+	Hs
		157202 CUL3_HUMAN (1-768): 0: 951: 100.00		BACH1_HUMAN (350-460): 4.83e-12: 72: 33.33
+	Hs
		196609 CUL3_HUMAN (1-768): 0: 951: 100.00		ZBT24_HUMAN (452-669): 3.63e-11: 69: 4.96
+	Hs
		1012650 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN816_HUMAN (723-787): 4.53e-09: 62: 35.39