HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: DNJA3 (Q96EY1)
DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog)
Gene: DNAJA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031398 - positive regulation of protein ubiquitination
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 480
+	Hs
		681439 CUL3_HUMAN (1-768): 0: 951: 100.00		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243399 CUL3_HUMAN (1-768): 0: 951: 100.00		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		1274015 CUL5_HUMAN (25-768): 0: 597: 23.77		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		681440 CUL4B_HUMAN (5-768): 0: 779: 36.77		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		681437 CUL1_HUMAN (18-768): 0: 707: 30.57		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		681438 CUL2_HUMAN (30-768): 0: 672: 26.17		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		681547 CUL5_HUMAN (25-768): 0: 597: 23.77		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43