HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: FGD4 (Q96M96)
FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament-binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6)
Gene: FGD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 766
+	Hs
		957981 CUL3_HUMAN (1-768): 0: 951: 100.00		FGD1_HUMAN (55-764): 9.97e-141: 440: 45.28
+	Hs
		1016910 CUL3_HUMAN (1-768): 0: 951: 100.00		AKP13_HUMAN (105-552): 6.89e-87: 303: 19.09
+	Hs
		1042210 CUL3_HUMAN (1-768): 0: 951: 100.00		ARHG2_HUMAN (105-528): 3.41e-85: 292: 18.40
+	Hs
		1042817 CUL3_HUMAN (1-768): 0: 951: 100.00		VAV3_HUMAN (122-685): 1.97e-85: 290: 14.72
+	Hs
		279863 CUL3_HUMAN (1-768): 0: 951: 100.00		TRIO_HUMAN (2-751): 1.96e-73: 263: 15.17
+	Hs
		855795 CUL4A_HUMAN (10-768): 0: 791: 38.32		VAV2_HUMAN (102-740): 2.27e-98: 326: 13.22
+	Hs
		224713 CUL4A_HUMAN (10-768): 0: 791: 38.32		KALRN_HUMAN (1-659): 6.6e-76: 270: 16.02