HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: IF140 (Q96RY7)
Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2)
Gene: IFT140

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 1462
+	Hs
		1042726 CUL3_HUMAN (1-768): 0: 951: 100.00		WDR35_HUMAN (66-1239): 0: 646: 11.53
+	Hs
		1043600 CUL4B_HUMAN (5-768): 0: 779: 36.77		IF122_HUMAN (54-937): 2.45e-81: 295: 12.84
+	Hs
		903207 CUL3_HUMAN (1-768): 0: 951: 100.00		WDR5_HUMAN (224-442): 2.08e-21: 99.3: 11.77
+	Hs
		1042655 CUL3_HUMAN (1-768): 0: 951: 100.00		NLE1_HUMAN (2-88): 4.99e-20: 97.4: 14.74
+	Hs
		254082 CUL3_HUMAN (1-768): 0: 951: 100.00		WDR1_HUMAN (2-218): 1.2e-18: 93.9: 8.96
+	Hs
		903208 CUL4A_HUMAN (10-768): 0: 791: 38.32		WDR5_HUMAN (224-442): 2.08e-21: 99.3: 11.77
+	Hs
		1016274 CUL4B_HUMAN (5-768): 0: 779: 36.77		TBL3_HUMAN (23-453): 8.08e-23: 107: 14.82
+	Hs
		903209 CUL4B_HUMAN (5-768): 0: 779: 36.77		WDR5_HUMAN (224-442): 2.08e-21: 99.3: 11.77
+	Hs
		903206 CUL1_HUMAN (18-768): 0: 707: 30.57		WDR5_HUMAN (224-442): 2.08e-21: 99.3: 11.77