HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	25684205, 20562859
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 117
+	Hs
		891133 CUL3_HUMAN (1-768): 0: 951: 100.00		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		306162 CUL3_HUMAN (1-768): 0: 951: 100.00		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		1042457 CUL3_HUMAN (1-768): 0: 951: 100.00		MLP3C_HUMAN (5-116): 1.61e-44: 143: 39.47
+	Hs
		1042492 CUL3_HUMAN (1-768): 0: 951: 100.00		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62