HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: SYSM (Q9NP81)
Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)
Gene: SARS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 518
+	Hs
		643748 CUL3_HUMAN (1-768): 0: 951: 100.00		SYTC_HUMAN (19-516): 1.51e-146: 439: 14.95
+	Hs
		829375 CUL3_HUMAN (1-768): 0: 951: 100.00		SYSC_HUMAN (58-513): 5.75e-143: 423: 23.43
+	Hs
		1042448 CUL3_HUMAN (1-768): 0: 951: 100.00		SYTM_HUMAN (22-478): 1.97e-116: 361: 16.83
+	Hs
		430944 CUL3_HUMAN (1-768): 0: 951: 100.00		SYEP_HUMAN (81-481): 1.15e-103: 341: 13.84
+	Hs
		1041210 CUL1_HUMAN (18-768): 0: 707: 30.57		SYSM_HUMAN (1-518): 0: 577: 100.00
+	Hs
		829376 CUL4A_HUMAN (10-768): 0: 791: 38.32		SYSC_HUMAN (58-513): 5.75e-143: 423: 23.43
+	Hs
		643747 CUL1_HUMAN (18-768): 0: 707: 30.57		SYTC_HUMAN (19-516): 1.51e-146: 439: 14.95
+	Hs
		1041895 CUL3_HUMAN (1-768): 0: 951: 100.00		SYPM_HUMAN (229-484): 1.8e-29: 122: 16.33
+	Hs
		430943 CUL1_HUMAN (18-768): 0: 707: 30.57		SYEP_HUMAN (81-481): 1.15e-103: 341: 13.84