HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 783
+	Hs
		1042393 CUL3_HUMAN (1-768): 0: 951: 100.00		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		1042199 CUL3_HUMAN (1-768): 0: 951: 100.00		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		134028 CUL3_HUMAN (1-768): 0: 951: 100.00		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571443 CUL3_HUMAN (1-768): 0: 951: 100.00		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Mm
		1207268 CUL3_MOUSE (1-768): 0: 949: 99.48		Q8BTS0_MOUSE (92-620): 1.47e-135: 416: 24.81
+	Hs
		1043244 CUL4A_HUMAN (10-768): 0: 791: 38.32		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1043604 CUL4B_HUMAN (5-768): 0: 779: 36.77		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		571444 CUL4A_HUMAN (10-768): 0: 791: 38.32		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		1043541 CUL4B_HUMAN (5-768): 0: 779: 36.77		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		1043492 CUL4B_HUMAN (5-768): 0: 779: 36.77		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		134029 CUL4B_HUMAN (5-768): 0: 779: 36.77		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571445 CUL4B_HUMAN (5-768): 0: 779: 36.77		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		1042608 CUL3_HUMAN (1-768): 0: 951: 100.00		DDX4_HUMAN (205-551): 1.96e-53: 199: 37.60
+	Hs
		757603 CUL3_HUMAN (1-768): 0: 951: 100.00		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		1041127 CUL1_HUMAN (18-768): 0: 707: 30.57		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		134026 CUL1_HUMAN (18-768): 0: 707: 30.57		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571441 CUL1_HUMAN (18-768): 0: 707: 30.57		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		134027 CUL2_HUMAN (30-768): 0: 672: 26.17		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571442 CUL2_HUMAN (30-768): 0: 672: 26.17		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		757602 CUL1_HUMAN (18-768): 0: 707: 30.57		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23