HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: ATD3A (Q9NVI7)
ATPase family AAA domain-containing protein 3A
Gene: ATAD3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 634
+	Hs
		1041758 CUL3_HUMAN (1-768): 0: 951: 100.00		ATD3B_HUMAN (1-634): 1.08e-122: 379: 86.59
+	Hs
		1042444 CUL3_HUMAN (1-768): 0: 951: 100.00		AFG2B_HUMAN (17-623): 1.1e-115: 364: 12.81
+	Hs
		913260 CUL3_HUMAN (1-768): 0: 951: 100.00		PRS10_HUMAN (226-605): 1.63e-97: 305: 19.10
+	Hs
		260139 CUL3_HUMAN (1-768): 0: 951: 100.00		VPS4B_HUMAN (356-629): 6.72e-74: 245: 23.66
+	Hs
		177499 CUL3_HUMAN (1-768): 0: 951: 100.00		NVL_HUMAN (117-631): 3.3e-54: 200: 13.22
+	Hs
		874907 CUL3_HUMAN (1-768): 0: 951: 100.00		TERA_HUMAN (44-365): 1.86e-44: 172: 9.20
+	Hs
		1042056 CUL3_HUMAN (1-768): 0: 951: 100.00		AFG2A_HUMAN (57-337): 1.74e-40: 160: 8.87
+	Hs
		1041222 CUL1_HUMAN (18-768): 0: 707: 30.57		ATD3A_HUMAN (1-634): 9.11e-132: 402: 100.00
+	Hs
		913261 CUL4A_HUMAN (10-768): 0: 791: 38.32		PRS10_HUMAN (226-605): 1.63e-97: 305: 19.10
+	Hs
		1135282 CUL5_HUMAN (25-768): 0: 597: 23.77		ATD3B_HUMAN (1-634): 1.08e-122: 379: 86.59
+	Hs
		874908 CUL4A_HUMAN (10-768): 0: 791: 38.32		TERA_HUMAN (44-365): 1.86e-44: 172: 9.20
+	Hs
		874909 CUL4B_HUMAN (5-768): 0: 779: 36.77		TERA_HUMAN (44-365): 1.86e-44: 172: 9.20
+	Hs
		874905 CUL1_HUMAN (18-768): 0: 707: 30.57		TERA_HUMAN (44-365): 1.86e-44: 172: 9.20
+	Dm
		1097193 CUL1_DROME (29-768): 0: 669: 27.49		TERA_DROME (40-365): 1.12e-46: 178: 8.49
+	Hs
		874906 CUL2_HUMAN (30-768): 0: 672: 26.17		TERA_HUMAN (44-365): 1.86e-44: 172: 9.20
+	Hs
		875192 CUL5_HUMAN (25-768): 0: 597: 23.77		TERA_HUMAN (44-365): 1.86e-44: 172: 9.20
+	Sc
		636771 CDC53_YEAST (30-768): 0: 573: 22.08		CDC48_YEAST (44-296): 2.03e-42: 165: 8.56