HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: PK1IP (Q9NWT1)
p21-activated protein kinase-interacting protein 1 (PAK/PLC-interacting protein 1) (hPIP1) (PAK1-interacting protein 1) (WD repeat-containing protein 84)
Gene: PAK1IP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	25011449
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 392
+	Hs
		1042655 CUL3_HUMAN (1-768): 0: 951: 100.00		NLE1_HUMAN (154-389): 4e-38: 144: 10.04
+	Hs
		1042101 CUL3_HUMAN (1-768): 0: 951: 100.00		POC1B_HUMAN (160-376): 2.68e-32: 128: 15.00
+	Hs
		903207 CUL3_HUMAN (1-768): 0: 951: 100.00		WDR5_HUMAN (202-377): 2.11e-30: 120: 13.66
+	Hs
		921555 CUL3_HUMAN (1-768): 0: 951: 100.00		GBB2_HUMAN (139-381): 1.14e-22: 99.5: 7.53
+	Hs
		152875 CUL3_HUMAN (1-768): 0: 951: 100.00		APAF_HUMAN (151-292): 6.2e-15: 78.6: 13.10
+	Hs
		1043319 CUL4A_HUMAN (10-768): 0: 791: 38.32		FBW1A_HUMAN (2-286): 6.86e-64: 216: 16.72
+	Hs
		792982 CUL4A_HUMAN (10-768): 0: 791: 38.32		LIS1_HUMAN (78-376): 3.91e-65: 214: 16.15
+	Hs
		1043297 CUL4A_HUMAN (10-768): 0: 791: 38.32		FBW1B_HUMAN (3-231): 7.86e-44: 161: 16.87
+	Hs
		1043114 CUL4A_HUMAN (10-768): 0: 791: 38.32		POC1B_HUMAN (160-376): 2.68e-32: 128: 15.00
+	Hs
		903208 CUL4A_HUMAN (10-768): 0: 791: 38.32		WDR5_HUMAN (202-377): 2.11e-30: 120: 13.66
+	Hs
		1043469 CUL4B_HUMAN (5-768): 0: 779: 36.77		POC1B_HUMAN (160-376): 2.68e-32: 128: 15.00
+	Hs
		903209 CUL4B_HUMAN (5-768): 0: 779: 36.77		WDR5_HUMAN (202-377): 2.11e-30: 120: 13.66
+	Hs
		1043234 CUL4A_HUMAN (10-768): 0: 791: 38.32		GBB4_HUMAN (159-381): 1.04e-22: 99.5: 7.34
+	Hs
		921556 CUL4A_HUMAN (10-768): 0: 791: 38.32		GBB2_HUMAN (139-381): 1.14e-22: 99.5: 7.53
+	Hs
		1043499 CUL4B_HUMAN (5-768): 0: 779: 36.77		FBXW7_HUMAN (1-146): 6.23e-26: 111: 19.48
+	Hs
		1043085 CUL4A_HUMAN (10-768): 0: 791: 38.32		WDR5B_HUMAN (237-374): 1.3e-14: 76: 11.45
+	Hs
		1043157 CUL4A_HUMAN (10-768): 0: 791: 38.32		SNR40_HUMAN (237-391): 4.8e-13: 71.8: 9.62
+	Hs
		152876 CUL4B_HUMAN (5-768): 0: 779: 36.77		APAF_HUMAN (151-292): 6.2e-15: 78.6: 13.10
+	Hs
		1043441 CUL4B_HUMAN (5-768): 0: 779: 36.77		WDR5B_HUMAN (237-374): 1.3e-14: 76: 11.45
+	Hs
		1043509 CUL4B_HUMAN (5-768): 0: 779: 36.77		SNR40_HUMAN (237-391): 4.8e-13: 71.8: 9.62