HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: HPBP1 (Q9NZL4)
Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2)
Gene: HSPBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031398 - positive regulation of protein ubiquitination GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 359
+	Hs
		853593 CUL3_HUMAN (1-768): 0: 951: 100.00		IMA5_HUMAN (51-301): 1.38e-24: 106: 15.02
+	Hs
		238673 CUL3_HUMAN (1-768): 0: 951: 100.00		IMA7_HUMAN (71-301): 3.77e-24: 105: 18.03
+	Hs
		134893 CUL3_HUMAN (1-768): 0: 951: 100.00		IMA3_HUMAN (57-331): 3.72e-21: 96.5: 14.39
+	Hs
		168634 CUL3_HUMAN (1-768): 0: 951: 100.00		IMA6_HUMAN (42-301): 2.31e-20: 94.2: 17.46
+	Hs
		853594 CUL4A_HUMAN (10-768): 0: 791: 38.32		IMA5_HUMAN (51-301): 1.38e-24: 106: 15.02
+	Hs
		134894 CUL4A_HUMAN (10-768): 0: 791: 38.32		IMA3_HUMAN (57-331): 3.72e-21: 96.5: 14.39
+	Hs
		853595 CUL4B_HUMAN (5-768): 0: 779: 36.77		IMA5_HUMAN (51-301): 1.38e-24: 106: 15.02
+	Hs
		134895 CUL4B_HUMAN (5-768): 0: 779: 36.77		IMA3_HUMAN (57-331): 3.72e-21: 96.5: 14.39
+	Hs
		853592 CUL1_HUMAN (18-768): 0: 707: 30.57		IMA5_HUMAN (51-301): 1.38e-24: 106: 15.02