HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: LRP1B (Q9NZR2)
Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)
Gene: LRP1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 4599
+	Hs
		1043623 CUL4B_HUMAN (5-768): 0: 779: 36.77		LRP1B_HUMAN (24-4599): 0: 3417: 100.00
+	Hs
		1042190 CUL3_HUMAN (1-768): 0: 951: 100.00		SORL_HUMAN (4318-4575): 1.89e-12: 76.8: 11.24
+	Hs
		957518 CUL3_HUMAN (1-768): 0: 951: 100.00		VLDLR_HUMAN (4316-4573): 2.68e-12: 75.6: 12.73
+	Hs
		804240 CUL3_HUMAN (1-768): 0: 951: 100.00		NOTC1_HUMAN (12-229): 5.06e-12: 75.3: 14.10
+	Hs
		1041541 CUL3_HUMAN (1-768): 0: 951: 100.00		NID2_HUMAN (4360-4522): 5.4e-12: 74.9: 10.66
+	Hs
		351068 CUL3_HUMAN (1-768): 0: 951: 100.00		LDLR_HUMAN (30-277): 8.85e-12: 74.1: 17.72
+	Hs
		957602 CUL3_HUMAN (1-768): 0: 951: 100.00		LRP2_HUMAN (4299-4586): 2.33e-10: 69.9: 9.18
+	Hs
		537517 CUL3_HUMAN (1-768): 0: 951: 100.00		NID1_HUMAN (3473-3718): 1.32e-09: 67.1: 13.83
+	Hs
		1041542 CUL3_HUMAN (1-768): 0: 951: 100.00		LRP8_HUMAN (4088-4430): 1.39e-09: 66.8: 9.81
+	Hs
		980368 CUL3_HUMAN (1-768): 0: 951: 100.00		NOTC2_HUMAN (11-260): 3.49e-09: 66: 14.40
+	Hs
		254259 CUL3_HUMAN (1-768): 0: 951: 100.00		LRP4_HUMAN (3711-3893): 9.84e-09: 64.5: 21.29
+	Hs
		992663 CUL3_HUMAN (1-768): 0: 951: 100.00		LRP1_HUMAN (5-268): 9.9e-09: 64.5: 14.24
+	Hs
		1041124 CUL1_HUMAN (18-768): 0: 707: 30.57		SORL_HUMAN (4318-4575): 1.89e-12: 76.8: 11.24