HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: ANFY1 (Q9P2R3)
Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif)
Gene: ANKFY1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	29038302, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 1169
+	Hs
		1043272 CUL4A_HUMAN (10-768): 0: 791: 38.32		ANFY1_HUMAN (1-1169): 0: 717: 100.00
+	Hs
		556700 CUL3_HUMAN (1-768): 0: 951: 100.00		ANK1_HUMAN (1-533): 2.33e-63: 239: 17.07
+	Hs
		166925 CUL3_HUMAN (1-768): 0: 951: 100.00		ANR28_HUMAN (871-1156): 6.5e-49: 191: 19.86
+	Hs
		1021397 CUL3_HUMAN (1-768): 0: 951: 100.00		ANK3_HUMAN (1-386): 1.03e-34: 147: 17.88
+	Hs
		1042054 CUL3_HUMAN (1-768): 0: 951: 100.00		ANR52_HUMAN (4-387): 7.32e-18: 91.8: 13.18
+	Hs
		1021398 CUL4A_HUMAN (10-768): 0: 791: 38.32		ANK3_HUMAN (1-386): 1.03e-34: 147: 17.88
+	Hs
		1274043 CUL5_HUMAN (25-768): 0: 597: 23.77		TNKS2_HUMAN (875-1127): 4.11e-47: 186: 18.82