HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: SAR1B (Q9Y6B6)
Small COPII coat GTPase SAR1B (EC 3.6.5.2) (GTP-binding protein B) (GTBPB) (Secretion-associated Ras-related GTPase 1B)
Gene: SAR1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0048208 - COPII vesicle coating
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 198
+	Hs
		574670 CUL3_HUMAN (1-768): 0: 951: 100.00		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		1042510 CUL3_HUMAN (1-768): 0: 951: 100.00		RAB1B_HUMAN (18-197): 5.27e-62: 192: 19.46
+	Hs
		950488 CUL3_HUMAN (1-768): 0: 951: 100.00		ARF1_HUMAN (1-197): 1.8e-59: 185: 26.90
+	Hs
		734462 CUL3_HUMAN (1-768): 0: 951: 100.00		ARL2_HUMAN (11-153): 2.4e-24: 95.9: 34.27
+	Hs
		1043210 CUL4A_HUMAN (10-768): 0: 791: 38.32		RAB1B_HUMAN (18-197): 5.27e-62: 192: 19.46