HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 30945288, 32140073, 31973889, 33961781, 21145461, 18593899, 36688959, 16964240, 23555860, 17041588
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~Cullin, Cullin~Cullin_Nedd8
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
GO:0016567 - protein ubiquitination
and 7 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 759
Hs

1 913
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024