HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: DC4L1 (Q3SXM0)
DDB1- and CUL4-associated factor 4-like protein 1 (WD repeat-containing protein 21B)
Gene: DCAF4L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26186194, 28514442, 33961781, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 759 Hs			1 396
+	Hs
		1043121 CUL4A_HUMAN (1-759): 0: 963: 100.00		DCAF4_HUMAN (1-396): 0: 691: 76.77
+	Hs
		1043107 CUL4A_HUMAN (1-759): 0: 963: 100.00		DC4L2_HUMAN (1-395): 0: 672: 73.92
+	Hs
		1043475 CUL4B_HUMAN (10-759): 0: 927: 82.31		DCAF4_HUMAN (1-396): 0: 691: 76.77
+	Hs
		1043460 CUL4B_HUMAN (10-759): 0: 927: 82.31		DC4L2_HUMAN (1-395): 0: 672: 73.92
+	Hs
		1043387 CUL4B_HUMAN (10-759): 0: 927: 82.31		DC4L1_HUMAN (1-396): 0: 668: 100.00