HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: LZTR1 (Q8N653)
Leucine-zipper-like transcriptional regulator 1 (LZTR-1)
Gene: LZTR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36688959
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 759 Hs			1 840
+	Hs
		1042036 CUL3_HUMAN (32-759): 0: 814: 38.23		LZTR1_HUMAN (1-840): 0: 613: 100.00
+	Hs
		214259 CUL4A_HUMAN (1-759): 0: 963: 100.00		SPOP_HUMAN (662-837): 6.69e-62: 215: 31.29
+	Hs
		1042971 CUL4A_HUMAN (1-759): 0: 963: 100.00		KEAP1_HUMAN (236-481): 2.95e-30: 129: 13.44
+	At
		80978 CUL3A_ARATH (36-759): 0: 853: 38.26		ABAP1_ARATH (618-830): 4.36e-62: 225: 25.23
+	At
		80974 CUL3B_ARATH (36-759): 0: 841: 37.99		ABAP1_ARATH (618-830): 4.36e-62: 225: 25.23
+	Hs
		1043271 CUL4A_HUMAN (1-759): 0: 963: 100.00		KLHL9_HUMAN (295-525): 1.35e-16: 86.2: 12.13
+	Hs
		1043391 CUL4B_HUMAN (10-759): 0: 927: 82.31		KLH12_HUMAN (1-186): 2.59e-28: 122: 18.82
+	Hs
		214258 CUL3_HUMAN (32-759): 0: 814: 38.23		SPOP_HUMAN (662-837): 6.69e-62: 215: 31.29
+	Hs
		1043281 CUL4A_HUMAN (1-759): 0: 963: 100.00		KLHL3_HUMAN (324-575): 1.65e-09: 63.4: 10.67
+	Hs
		1041807 CUL3_HUMAN (32-759): 0: 814: 38.23		KLH10_HUMAN (650-837): 9.12e-47: 179: 21.16
+	Hs
		848213 CUL3_HUMAN (32-759): 0: 814: 38.23		HCFC1_HUMAN (104-467): 7.65e-45: 177: 17.16
+	Hs
		1042324 CUL3_HUMAN (32-759): 0: 814: 38.23		KLHL5_HUMAN (4-237): 5.73e-40: 160: 20.94
+	Hs
		1042624 CUL3_HUMAN (32-759): 0: 814: 38.23		KLHL1_HUMAN (238-525): 1.38e-39: 159: 13.75
+	Hs
		299515 CUL3_HUMAN (32-759): 0: 814: 38.23		KLH18_HUMAN (224-452): 6.99e-34: 139: 13.81
+	Rn
		78189 CUL3_RAT (32-759): 0: 814: 38.36		KLH17_RAT (218-456): 1.7e-31: 133: 13.75
+	Hs
		1041547 CUL3_HUMAN (32-759): 0: 814: 38.23		KEAP1_HUMAN (236-481): 2.95e-30: 129: 13.44
+	Hs
		1041712 CUL3_HUMAN (32-759): 0: 814: 38.23		KLH12_HUMAN (1-186): 2.59e-28: 122: 18.82
+	Hs
		1042489 CUL3_HUMAN (32-759): 0: 814: 38.23		KLHL4_HUMAN (5-127): 8.72e-16: 83.9: 18.70
+	Hs
		1042070 CUL3_HUMAN (32-759): 0: 814: 38.23		RCBT1_HUMAN (665-821): 1.6e-15: 82.4: 28.66
+	Hs
		1041852 CUL3_HUMAN (32-759): 0: 814: 38.23		KLH17_HUMAN (324-525): 7.51e-11: 67.7: 10.84