Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: TP4AP (Q8TEL6)
Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS)
Gene: TRPC4AP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.746

The method score is based on:

Property Details
Experiments 28514442, 33961781, 37689310, 20551172, 31973889, 16964240, 21145461
Identification Methods affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0016567 - protein ubiquitination
GO:0031464 - Cul4A-RING E3 ubiquitin ligase complex
GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
GO:0140627 - ubiquitin-dependent protein catabolic process via the C-end degron rule pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 759
Hs

1 797
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024