HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18381890
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008283 - cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 759 Hs			1 1164
+	Hs
		1042177 CUL3_HUMAN (32-759): 0: 814: 38.23		TSC1_HUMAN (1-1164): 0: 725: 100.00
+	Mm
		1322212 CUL3_MOUSE (32-759): 0: 813: 38.36		TSC1_MOUSE (1-1164): 0: 695: 86.98
+	Hs
		1042974 CUL4A_HUMAN (1-759): 0: 963: 100.00		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		1035170 CUL4A_HUMAN (1-759): 0: 963: 100.00		ROCK1_HUMAN (433-926): 6.18e-15: 82.2: 12.00
+	Hs
		1043487 CUL4B_HUMAN (10-759): 0: 927: 82.31		MY18A_HUMAN (461-1064): 4e-25: 115: 10.31
+	Hs
		1041558 CUL3_HUMAN (32-759): 0: 814: 38.23		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		725158 CUL4A_HUMAN (1-759): 0: 963: 100.00		MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43
+	Hs
		1042182 CUL3_HUMAN (32-759): 0: 814: 38.23		MY18A_HUMAN (461-1064): 4e-25: 115: 10.31
+	Hs
		254479 CUL3_HUMAN (32-759): 0: 814: 38.23		ROCK2_HUMAN (415-1038): 1.55e-24: 113: 11.27
+	Hs
		724816 CUL3_HUMAN (32-759): 0: 814: 38.23		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		148780 CUL3_HUMAN (32-759): 0: 814: 38.23		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		551697 CUL3_HUMAN (32-759): 0: 814: 38.23		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		1042944 CUL3_HUMAN (32-759): 0: 814: 38.23		MRCKB_HUMAN (835-1162): 1.41e-15: 84.5: 6.67
+	Hs
		1035169 CUL3_HUMAN (32-759): 0: 814: 38.23		ROCK1_HUMAN (433-926): 6.18e-15: 82.2: 12.00
+	Hs
		1041911 CUL3_HUMAN (32-759): 0: 814: 38.23		MYH14_HUMAN (620-918): 1.78e-11: 71.1: 13.11
+	Hs
		725157 CUL3_HUMAN (32-759): 0: 814: 38.23		MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43
+	Hs
		724815 CUL1_HUMAN (59-759): 0: 745: 30.55		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		502913 CUL1_HUMAN (59-759): 0: 745: 30.55		MYH3_HUMAN (400-850): 1.77e-10: 67.9: 10.00
+	Hs
		969583 CUL1_HUMAN (59-759): 0: 745: 30.55		CENPE_HUMAN (620-984): 9.03e-10: 65.5: 20.36
+	Hs
		725156 CUL1_HUMAN (59-759): 0: 745: 30.55		MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43